AboutFolate is the generic term used to describe the water-soluble, B-complex vitamins including Folic Acid and other naturally occurring folate; tetrahydrofolate can be found as the active form in the body. Folate acts as a coenzyme in numerous essential metabolic processes. Folic Acid plays a key role in proper growth and optimal functioning of bone marrow, cell division, and lowering the risk of many health conditions, including cardiovascular disease. It is especially important during pregnancy for the development of the baby’s nervous system and the prevention of NTD’s. Deficiency of this vitamin is common in many parts of the world and requires supplementation, however, if you have the MTHFR mutation, you should not take Folic Acid in this form (see Methylfolate).